Exploring the Chemistry and Biology of Nucleic Acids
PhDs and Postdocs wanted for exciting i) G-quadruplex, ii) RNA, and iii) aptamer projects!
Email (ckkwok42@cityu.edu.hk) with CV and research background if interested.
Email (ckkwok42@cityu.edu.hk) with CV and research background if interested.
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What our lab studies: - G-quadruplex Structure and Function - RNA Biology and Gene Regulation - Aptamer and NGS Development Funding sources:
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Recent publications: Mou, X., Liew, S. W. & Kwok, C.K. Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA. Nucleic Acids Res. 50, 397- 410 (2022). Dumetz, F., Chow, E.Y.C. et al. G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum. Nucleic Acids Res. 49, 12486–12501 (2021). Chen, X., Yuan, J., Xue, G. et al. Translational control by DHX36 binding to 5’UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nat Commun 12, 5043 (2021). Ji, D., Lyu, K., Zhao, H. & Kwok, C.K. Circular L-RNA aptamer promotes target recognition and controls gene activity. Nucleic Acids Res. 49, 7280-7291 (2021). Zhang, Y., Wu, Y., Zheng, H., Xi, H., Ye, T., Chan, C. Y. & Kwok, C.K. Proteomic and Transcriptome Profiling of G-Quadruplex Aptamers Developed for Cell Internalization. Anal. Chem. 93, 5744-5753 (2021). Lyu, K., Chow, E.Y.C., Mou, X., Chan, T. & Kwok, C.K. RNA G-quadruplexes (rG4s): genomics and biological functions. Nucleic Acids Res. 49, 5426-5450 (2021). Zhao, H. & Kwok, C.K. Bringing distant DNA together. Nature Chem. Bio. 17, 125-126 (2021). |
Recent lab news: Jan 2022: A big welcome to Kelly as a new UG of Kwok Lab! Dec 2021: Paper published in Nucleic Acids Research! Congrats to Xi and Caroline! Nov 2021: New paper published in Nucleic Acids Research! Congratulations to Caroline and Mubarak! Sep 2021: Welcome Beijia as a new UG member of Kwok Lab! Aug 2021: Our new paper is now online in Nature Communications! Congratulations to Xi, Caroline and Mubarak! Jul 2021: Farewell! Best wishes to your postdoc journey, Mubarak! Jul 2021: Paper published in Nucleic Acids Research! Congrats to Danyang, Kaixin and Haizhou! Jul 2021: Congratulations to Dr Kwok on the promotion! May 2021: Happy Graduation to our undergraduates Caroline and Phoebe! Congratulations! March 2021: Our new paper is now published in Analytical Chemistry. Congrats to Jamie! March 2021: Paper published in Nucleic Acids Research! Congrats to Kaixin and Xi! |