Exploring the Chemistry & Biology of Nucleic Acids
PhDs/Postdocs wanted for G-quadruplex, RNA, and aptamer projects!
Email Prof. Kwok with your CV and research background.
Email Prof. Kwok with your CV and research background.
|
What our lab studies: - G-quadruplex Structure and Function - RNA Biology and Gene Regulation - Aptamer Development and Application Funding sources:
|
Recent publications: Yarshova, M., Zhao, J., Kwok, C. K. Recent Advance in Chemical Probing Strategies for RNA Structure Determination in Vivo. Chem. Eur. J., e03291. (2026). Wan, W., Ji, X., Song, H., Zhang, Z., Kwok, C. K., Fang, X., & Li, X. Fluorogenic CRISPR for DNA imaging in live mammalian cells. Cell Chem. Biol., 33(1), 33-44. (2026). Liu, G., Wu, T. Y., Kwok, C. K., & Liu, J. Computational Analysis Uncovering Contrasts in G-Quadruplex Propensity and Aptamer Enrichment in SELEX-Derived Libraries. Chembiochem., 27(1), e202500614 (2025). Zhou, Y., Lyu, S., Liew, S. W., Mou, X., Hoffecker, I., Yan, J., Li, Y., Kwok, C. K., & Zhang, J. MoRNiNG: A Database of RNA Modification Sites Associated with RNA Secondary Structure Dynamics. GPB. qzaf106 (2025). Zhang, F., Liew, S. W., Lam, S. Y., & Kwok, C. K. Nucleic acid-guided protein-empowered aquatic contaminants sensing. Trends Chem. 7 (12), 853-868 (2025). Ji, D., Zhang, K., Yarshova, M., Kwok, C. K. L-RNA Aptamer-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Applications. Acc. Chem. Res. 58 (21), 3247-3258 (2025). Chow, E. Y.-C., Zhao, J., Kwok, C. K., & Chan, T.-F. Differential Evolution of CDS and UTR Non-canonical RNA G-quadruplex Structures in Eukaryotic Transcriptomes. GPB. Qzaf078 (2025). |
Recent lab news: Jan 2026: Farewell, Xi! Jan 2026: Paper published in Chemistry: A European Journal. Congrats to Maryana and Jieyu! Dec 2025: Collaboration Paper published in Chembiochem. Congrats to Tianying! Nov 2025: Collaboration Paper published in Genomics, Proteomics & Bioinformatics. Congrats to Caroline and Xi! Oct 2025: Paper published in Trends in Chemistry. Congrats to Beatrice and Caroline! Sep 2025: Congrats to Rachelle for being awarded the Hong Kong Life Sciences Scholarship 2025/26! Sep 2025: Paper published in Accounts of Chemical Research. Congrats to Kun and Maryana! Sep 2025: Collaboration Paper published in Genomics, Proteomics & Bioinformatics. Congrats to Jieyu! Sep 2025: Collaboration Paper published in Nucleic Acid Research. Congrats to Jieyu! Aug 2025: Collaboration Paper published in Genome Research. Congrats to Caroline! |