Exploring the Chemistry & Biology of Nucleic Acids
PhDs/Postdocs wanted for G-quadruplex, RNA, and aptamer projects!
Email Prof. Kwok with your CV and research background.
Email Prof. Kwok with your CV and research background.
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What our lab studies: - G-quadruplex Structure and Function - RNA Biology and Gene Regulation - Aptamer Development and Application Funding sources:
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Recent publications: Zhang, F., Liew, S. W., Lam, S. Y., & Kwok, C. K. Nucleic acid-guided protein-empowered aquatic contaminants sensing. Trends Chem. (2025). Ji, D., Zhang, K., Yarshova, M., Kwok, C. K. L-RNA Aptamers-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Applications. Acc. Chem. Res. 58 (21), 3247–3258 (2025). Chow, E. Y.-C., Zhao, J., Kwok, C. K., & Chan, T.-F. Differential Evolution of CDS and UTR Non-canonical RNA G-quadruplex Structures in Eukaryotic Transcriptomes. GPB. Qzaf078 (2025). Chen, X., Yang, F., Zhang, S., Guo, X., Zhao, J., Qiao, Y., He, L., Li, Y., Zhou, Q., Ong, M. T.-Y., Kwok, C. K., Sun, H., Wang, H. DNA G-quadruplex profiling in skeletal muscle stem cells reveals functional and mechanistic insights. Genome Biol. 26, 269(2025). Zhao, J., Yang, F., Zhang, Y., Wang, H., Kwok, C. K. TDP-43 binds to RNA G-quadruplex structure and regulates mRNA stability and translation. Nucleic Acids Res. 53(16), gkaf820 (2025). Chantzi, N., Nayak, A., Baltoumas, F. A., Aplakidou, E., Liew, S. W., Galuh, J. E., Patsakis, M., Montgomery, A., Moeckel, C., Mouratidis, I., Sazed, S. A., Guiblet, W., Karmiris-Obratański, P., Wang, G., Zaravinos, A., Vasquez, K. M., Kwok, C. K., Pavlopoulos, G. A., & Georgakopoulos-Soares, I. Quadrupia provides a comprehensive catalog of G-quadruplexes across genomes from the tree of life. Genome Res. 35(11), 2578-2600 (2025). |
Recent lab news: Oct 2025: Paper published in Trends in Chemistry. Congrats to Beatrice and Caroline! Sep 2025: Congrats to Rachelle for being awarded the Hong Kong Life Sciences Scholarship 2025/26! Sep 2025: Paper published in Accounts of Chemical Research. Congrats to Kun and Maryana! Sep 2025: Collaboration Paper published in Genomics, Proteomics & Bioinformatics. Congrats to Jieyu! Sep 2025: Collaboration Paper published in Nucleic Acid Research. Congrats to Jieyu! Aug 2025: Collaboration Paper published in Genome Research. Congrats to Caroline! Aug 2025: Farewell, Fang! Jul 2025: Paper published in Organic & Biomolecular. Chemistry. Congrats to Tianying! Jun 2025: Paper published in RNA. Congrats to Tianying, Kelly, and Rachelle! Apr 2025: Farewell, Aurell! Mar 2025: Paper published in Analytical Chemistry. Congrats to Beatrice! |