Exploring the Chemistry & Biology of Nucleic Acids
PhDs/Postdocs wanted for G-quadruplex, RNA, and aptamer projects!
Email Prof. Kwok with your CV and research background.
Email Prof. Kwok with your CV and research background.
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What our lab studies: - G-quadruplex Structure and Function - RNA Biology and Gene Regulation - Aptamer Development and Application Funding sources:
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Recent publications: Huang, S., Zeng, H., Wu, A., Zhao, M., Pan, N., Liu, Z., Wang, R., Chen, S., Wang, L., Kwok, C. K. & Zhang, F. A highly sensitive universal modularized CRISPR/Cas14a system for antibiotic sensing. Sens. Actuator B-Chem. 139657. (2026). Yarshova, M., Zhao, J., Kwok, C. K. Recent Advance in Chemical Probing Strategies for RNA Structure Determination in Vivo. Chem. Eur. J. 32(12), e03291. (2026). Wan, W., Ji, X., Song, H., Zhang, Z., Kwok, C. K., Fang, X., & Li, X. Fluorogenic CRISPR for DNA imaging in live mammalian cells. Cell Chem. Biol. 33(1), 33-44. (2026). Liu, G., Wu, T. Y., Kwok, C. K., & Liu, J. Computational Analysis Uncovering Contrasts in G-Quadruplex Propensity and Aptamer Enrichment in SELEX-Derived Libraries. Chembiochem. 27(1), e202500614 (2026). Zhou, Y., Lyu, S., Liew, S. W., Mou, X., Hoffecker, I., Yan, J., Li, Y., Kwok, C. K., & Zhang, J. MoRNiNG: A Database of RNA Modification Sites Associated with RNA Secondary Structure Dynamics. GPB. qzaf106 (2025). Zhang, F., Liew, S. W., Lam, S. Y., & Kwok, C. K. Nucleic acid-guided protein-empowered aquatic contaminants sensing. Trends Chem. 7 (12), 853-868 (2025). Ji, D., Zhang, K., Yarshova, M., Kwok, C. K. L-RNA Aptamer-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Applications. Acc. Chem. Res. 58 (21), 3247-3258 (2025). |
Recent lab news: Mar 2026: Congrats to Caroline and Beatrice for winning the bronze medal at the 51st International Exhibition of Inventions Geneva! Feb 2026: Collaboration Paper published in Sensors and Actuators B: Chemical. Congrats to Fang! Jan 2026: Farewell, Xi! Jan 2026: Paper published in Chemistry: A European Journal. Congrats to Maryana and Jieyu! Dec 2025: Collaboration Paper published in Chembiochem. Congrats to Tianying! Nov 2025: Collaboration Paper published in Genomics, Proteomics & Bioinformatics. Congrats to Caroline and Xi! Oct 2025: Paper published in Trends in Chemistry. Congrats to Beatrice and Caroline! Sep 2025: Congrats to Rachelle for being awarded the Hong Kong Life Sciences Scholarship 2025/26! Sep 2025: Paper published in Accounts of Chemical Research. Congrats to Kun and Maryana! Sep 2025: Collaboration Paper published in Genomics, Proteomics & Bioinformatics. Congrats to Jieyu! |