Exploring the Chemistry and Biology of Nucleic Acids
PhDs and Postdocs wanted for exciting i) G-quadruplex, ii) RNA, and iii) aptamer projects!
Email (ckkwok42@cityu.edu.hk) with CV and research background if interested.
Email (ckkwok42@cityu.edu.hk) with CV and research background if interested.
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What our lab studies: - G-quadruplex Structure and Function - RNA Biology and Gene Regulation - Aptamer Development and Application Funding sources:
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Recent publications: Guo, W., Ji, D., Kinghorn, A. B., Chen, F., Pan, Y., Li, X., Li, Q., Huck, W. T. S., Kwok, C.K, Shum, H. C. Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates. JACS. 145, 2375-2385 (2023). Lam, S.Y., Lau, H.L., Kwok, C.K. Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application. Biosensors. 12(12), 1142 (2022). Lyu, K, Chen, S.B., Chow, E.Y., Zhao, H., Yuan, J.H., Cai, M., Shi, J., Chan, T.F., Tan, J.H., Kwok, C.K. An RNA G-Quadruplex Structure within the ADAR 5'UTR Interacts with DHX36 Helicase to Regulate Translation. Angewandte Chemie. 61, e20203553 (2022). Zhao, J., Chow, E.U., Yeung, P.Y., Zhang, Q.C., Chan, T.F., Kwok, C.K. Enhanced transcriptome-wide RNA G-Quadruplex sequencing for low RNA input samples with rG4-seq 2.0. BMC Biology. 20, 257 (2022). Yang, X., Yu, H., Duncan, S., Zhang, Y., Cheema, J., Liu, H., Miller, J.B., Zhang, J., Kwok, C.K., Zhang, H., Ding, Y. RNA G-quadruplex structure contributes to cold adaptation in plants. Nat Commun. 13, 6224 (2022). Dumetz, F., Enright, A.J., Zhao, J., Kwok, C.K, Merrick, C.J. The in vivo RNA structurome of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome. Plos One. 17(9), e0270863 (2022). Zhang, Y., Juhas, M., Kwok, C. K. Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19. Trends in Biotechnology. DOI: https://doi.org/10.1016/j.tibtech.2022.07.012 |
Recent lab news: Mar 2023: CSCI Excellent Paper Award. Congrats to Danyang! Feb 2023: Congrats to Beatrice, Danyang and Sharon for securing HK Tech 300 and HKSTP Ideation Fund! Jan 2023: CSCI Excellent Paper Award. Congrats to Kaixin! Jan 2023: Paper published in JACS. Congrats to Danyang! Dec 2022: Paper published in Biosensors. Congrats to Beatrice and Kelly! Nov 2022: Paper published in Angewandte Chemie. Congrats to Kaixin and Haizhou! Nov 2022: Paper published in BMC Biology. Congrats to Jieyu! Sep 2022: Paper published in Plos One. Congrats to Jieyu! Jun 2022: Paper published in ACS Applied Materials & Interfaces! Congrats to Haizhou, Phoebe, Danyang and Kaixin! Jun 2022: Graduation of our undergraduate Kelly! Congratulations! Jun 2022: Paper published in Cell Reports! Congrats to Jieyu! May 2022: Congratulations to Beatrice for winning the Merit Prize of 'The 8th Hong Kong University Student Innovation and Entrepreneurship Competition'! |