Google Scholar link PUBMED link
2022
58. Lyu, K, Chen, S.B., Chow, E.Y., Zhao, H., Yuan, J.H., Cai, M., Shi, J., Chan, T.F., Tan, J.H., Kwok, C.K. An RNA G-Quadruplex Structure within the ADAR 5'UTR Interacts with DHX36 Helicase to Regulate Translation. Angewandte Chemie. e20203553 (2022).
57. Zhao, J., Chow, E.U., Yeung P.Y., Zhang, Q.C., Chan, T.F., Kwok C.K. Enhanced transcriptome-wide RNA G-Quadruplex sequencing for low RNA input samples with rG4-seq 2.0. BMC Biology. 20, 257 (2022).
56. Yang, X., Yu, H., Duncan, S., Zhang, Y., Cheema, J., Liu, H., Miller, J.B., Zhang, J., Kwok, C.K., Zhang, H., Ding, Y. RNA G-quadruplex structure contributes to cold adaptation in plants. Nat Commun. 13, 6224 (2022).
55. Dumetz, F., Enright, A.J., Zhao, J., Kwok, C. K, Merrick, C.J. The in vivo RNA structuromone of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome. Plos One. 17(9), e0270863 (2022).
54. Zhang, Y., Juhas, M., Kwok, C. K. Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19. Trends in Biotechnology. DOI: https://doi.org/10.1016/j.tibtech.2022.07.012 (2022).
53. Zhao, H., Wong, H.Y., Ji, D., Lyu, K. & Kwok, C.K. Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure. ACS Appl. Mater. Interfaces. 14, 30582- 30594 (2022).
52. Chen, X., Xue, G., Zhao, J., Zhang, Y., Zhang, Z., Wang, W., Li, Y., Yuan, J., He, J., Chan, C.Y., Liu, Y., Chen, W., Zhao, Y., Hu, P., Sun, H., Kwok, C.K. & Wang, H. Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5′ UTR rG4 unwinding and Anp32e translation. Cell Rep. 39, 110927 (2022).
51. Georgakopoulos-Soares, I., Parada, G.E., Wong, H.Y., Medhi, R., Furlan, G., Munita, R., Miska, E.A., Kwok, C.K. & Hemberg, M. Alternative splicing modulation by G-quadruplexes. Nat Commun 13, 2404 (2022).
50. Xu, B., Zhu, Y., Cao, C., Chen, H., Jin, Q., Li, G., Ma, J., Zhao, J., Zhu, J., Ding, Y., Fang, X., JIN, Y., Kwok, C.K., Ren, A., Wan, Y., Wang, Z., Xue, Y., Zhang, H., Zhang, Q. & Zhou,Y. Recent advances in RNA structurome. SCIENCE CHINA Life Sciences. 65, 1285- 1324 (2022).
49. Umar, M.I., Chan, CY. & Kwok, C.K. Development of RNA G-quadruplex (rG4)-targeting L-RNA aptamers by rG4-SELEX. Nat Protoc. 17, 1385-1414 (2022).
48. Georgakopoulos-Soares, I., Victorino, J., Parada, G.E., Agarwal, V., Zhao, J., Wong, H.Y., Umar, M,I., Elor, O., Muhwezi, A., An, J., Sanders, S.J., Kwok, C.K., Inoue, F., Hemberg, M. & Ahituv, N. High-throughput characterization of the role of non-B DNA motifs on promoter function. Cell Genomics. 2, 100111 (2022).
47. Feng, H, & Kwok, C.K. Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures. RSC Chem. Biol. 3, 431- 435 (2022).
46. Piao, M., Li, P., Zeng, X., Wang, X., Kang, L., Zhang, J., Wei, Y., Zhang, S., Tang, L., Zhu, J., Kwok, C.K., Hu, X. & Zhang, Q.F.C. An ultra low-input method for global RNA structure probing uncovers Regnase-1-mediated regulation in macrophages. Fundamental Research. 2, 2-13 (2022).
45. Mou, X., Liew, S. W. & Kwok, C.K. Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA. Nucleic Acids Res. 50, 397- 410 (2022).
57. Zhao, J., Chow, E.U., Yeung P.Y., Zhang, Q.C., Chan, T.F., Kwok C.K. Enhanced transcriptome-wide RNA G-Quadruplex sequencing for low RNA input samples with rG4-seq 2.0. BMC Biology. 20, 257 (2022).
56. Yang, X., Yu, H., Duncan, S., Zhang, Y., Cheema, J., Liu, H., Miller, J.B., Zhang, J., Kwok, C.K., Zhang, H., Ding, Y. RNA G-quadruplex structure contributes to cold adaptation in plants. Nat Commun. 13, 6224 (2022).
55. Dumetz, F., Enright, A.J., Zhao, J., Kwok, C. K, Merrick, C.J. The in vivo RNA structuromone of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome. Plos One. 17(9), e0270863 (2022).
54. Zhang, Y., Juhas, M., Kwok, C. K. Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19. Trends in Biotechnology. DOI: https://doi.org/10.1016/j.tibtech.2022.07.012 (2022).
53. Zhao, H., Wong, H.Y., Ji, D., Lyu, K. & Kwok, C.K. Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure. ACS Appl. Mater. Interfaces. 14, 30582- 30594 (2022).
52. Chen, X., Xue, G., Zhao, J., Zhang, Y., Zhang, Z., Wang, W., Li, Y., Yuan, J., He, J., Chan, C.Y., Liu, Y., Chen, W., Zhao, Y., Hu, P., Sun, H., Kwok, C.K. & Wang, H. Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5′ UTR rG4 unwinding and Anp32e translation. Cell Rep. 39, 110927 (2022).
51. Georgakopoulos-Soares, I., Parada, G.E., Wong, H.Y., Medhi, R., Furlan, G., Munita, R., Miska, E.A., Kwok, C.K. & Hemberg, M. Alternative splicing modulation by G-quadruplexes. Nat Commun 13, 2404 (2022).
50. Xu, B., Zhu, Y., Cao, C., Chen, H., Jin, Q., Li, G., Ma, J., Zhao, J., Zhu, J., Ding, Y., Fang, X., JIN, Y., Kwok, C.K., Ren, A., Wan, Y., Wang, Z., Xue, Y., Zhang, H., Zhang, Q. & Zhou,Y. Recent advances in RNA structurome. SCIENCE CHINA Life Sciences. 65, 1285- 1324 (2022).
49. Umar, M.I., Chan, CY. & Kwok, C.K. Development of RNA G-quadruplex (rG4)-targeting L-RNA aptamers by rG4-SELEX. Nat Protoc. 17, 1385-1414 (2022).
48. Georgakopoulos-Soares, I., Victorino, J., Parada, G.E., Agarwal, V., Zhao, J., Wong, H.Y., Umar, M,I., Elor, O., Muhwezi, A., An, J., Sanders, S.J., Kwok, C.K., Inoue, F., Hemberg, M. & Ahituv, N. High-throughput characterization of the role of non-B DNA motifs on promoter function. Cell Genomics. 2, 100111 (2022).
47. Feng, H, & Kwok, C.K. Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures. RSC Chem. Biol. 3, 431- 435 (2022).
46. Piao, M., Li, P., Zeng, X., Wang, X., Kang, L., Zhang, J., Wei, Y., Zhang, S., Tang, L., Zhu, J., Kwok, C.K., Hu, X. & Zhang, Q.F.C. An ultra low-input method for global RNA structure probing uncovers Regnase-1-mediated regulation in macrophages. Fundamental Research. 2, 2-13 (2022).
45. Mou, X., Liew, S. W. & Kwok, C.K. Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA. Nucleic Acids Res. 50, 397- 410 (2022).
2021
44. Dumetz, F., Chow, E.Y.C., Harris, L.M., Liew, S.W., Jensen, A., Umar, M.I., Chung, B., Chan, T.F., Merrick, C.J. & Kwok, C.K. G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum. Nucleic Acids Res. 49, 12486–12501 (2021).
43. Chen, X., Yuan, J., Xue, G., Campanario, S., Wang, D., Wang, W., Mou, X., Liew, S.W., Umar, M.I., Isern, J., Zhao, Y., He, L., Li, Y., Mann, C.J., Yu, X., Wang, L., Perdiguero, E., Chen, W., Xue, Y., Nagamine, Y., Kwok, C.K., Sun, H., Muñoz-Cánoves, P. & Wang, H. Translational control by DHX36 binding to 5’UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nat Commun 12, 5043 (2021).
42. Ji, D., Lyu, K., Zhao, H. & Kwok, C.K. Circular L-RNA aptamer promotes target recognition and controls gene activity. Nucleic Acids Res. 49, 7280-7291 (2021).
41. Zhang, Y., Wu, Y., Zheng, H., Xi, H., Ye, T., Chan, C. Y. & Kwok, C.K. Proteomic and Transcriptome Profiling of G-Quadruplex Aptamers Developed for Cell Internalization. Anal. Chem. 93, 5744-5753 (2021).
40. Lyu, K., Chow, E.Y.C., Mou, X., Chan, T. & Kwok, C.K. RNA G-quadruplexes (rG4s): genomics and biological functions. Nucleic Acids Res. 49, 5426-5450 (2021).
39. Zhao, H. & Kwok, C.K. Bringing distant DNA together. Nature Chem. Bio. 17, 125-126 (2021).
43. Chen, X., Yuan, J., Xue, G., Campanario, S., Wang, D., Wang, W., Mou, X., Liew, S.W., Umar, M.I., Isern, J., Zhao, Y., He, L., Li, Y., Mann, C.J., Yu, X., Wang, L., Perdiguero, E., Chen, W., Xue, Y., Nagamine, Y., Kwok, C.K., Sun, H., Muñoz-Cánoves, P. & Wang, H. Translational control by DHX36 binding to 5’UTR G-quadruplex is essential for muscle stem-cell regenerative functions. Nat Commun 12, 5043 (2021).
42. Ji, D., Lyu, K., Zhao, H. & Kwok, C.K. Circular L-RNA aptamer promotes target recognition and controls gene activity. Nucleic Acids Res. 49, 7280-7291 (2021).
41. Zhang, Y., Wu, Y., Zheng, H., Xi, H., Ye, T., Chan, C. Y. & Kwok, C.K. Proteomic and Transcriptome Profiling of G-Quadruplex Aptamers Developed for Cell Internalization. Anal. Chem. 93, 5744-5753 (2021).
40. Lyu, K., Chow, E.Y.C., Mou, X., Chan, T. & Kwok, C.K. RNA G-quadruplexes (rG4s): genomics and biological functions. Nucleic Acids Res. 49, 5426-5450 (2021).
39. Zhao, H. & Kwok, C.K. Bringing distant DNA together. Nature Chem. Bio. 17, 125-126 (2021).
2020
38. Mou, X. & Kwok, C.K. Effect of RNA sequence context and stereochemistry on G-quadruplex-RHAU53 interaction. Biochem. Biophys. Res. Commun. 533, 1135-1141 (2020).
37. Umar, M.I. & Kwok, C.K. Specific suppression of D-RNA G-quadruplex–protein interaction with an L-RNA aptamer. Nucleic Acids Res. 48, 10125-10141 (2020).
36. Yang, X., Cheema, J., Zhang, Y., Deng, H., Duncan, S., Umar, M. I., Zhao, J., Liu, Q., Cao, X., Kwok, C. K. & Ding, Y. RNA G-quadruplex structures exist and function in vivo in plants. Genome Biol 21, 226 (2020).
35. Ji, D., Juhas, M., Tsang, C. M., Kwok, C. K., Li, Y. & Zhang, Y. Discovery of G-quadruplex-forming sequences in SARS-CoV-2. Briefings in Bioinformatics 22, 1150-1160 (2020).
34. Chow, E.Y.C., Lyu, K., Kwok, C. K. & Chan, T.F. rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments. RNA Biology 17, 903-917 (2020).
33. Chan, C. Y., & Kwok, C. K. Specific Binding of a D‐RNA G‐Quadruplex Structure with an L‐RNA Aptamer. Angew. Chem. Int. Ed. 59, 5293 –5297 (2020).
32. Shao, X., Zhang, W., Umar, M. I., Wong, H. Y., Seng, Z., Xie, Y., Zhang, Y., Yang, L., Kwok, C. K. & Deng, X. RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria. mBio 11, 1 (2020).
37. Umar, M.I. & Kwok, C.K. Specific suppression of D-RNA G-quadruplex–protein interaction with an L-RNA aptamer. Nucleic Acids Res. 48, 10125-10141 (2020).
36. Yang, X., Cheema, J., Zhang, Y., Deng, H., Duncan, S., Umar, M. I., Zhao, J., Liu, Q., Cao, X., Kwok, C. K. & Ding, Y. RNA G-quadruplex structures exist and function in vivo in plants. Genome Biol 21, 226 (2020).
35. Ji, D., Juhas, M., Tsang, C. M., Kwok, C. K., Li, Y. & Zhang, Y. Discovery of G-quadruplex-forming sequences in SARS-CoV-2. Briefings in Bioinformatics 22, 1150-1160 (2020).
34. Chow, E.Y.C., Lyu, K., Kwok, C. K. & Chan, T.F. rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments. RNA Biology 17, 903-917 (2020).
33. Chan, C. Y., & Kwok, C. K. Specific Binding of a D‐RNA G‐Quadruplex Structure with an L‐RNA Aptamer. Angew. Chem. Int. Ed. 59, 5293 –5297 (2020).
32. Shao, X., Zhang, W., Umar, M. I., Wong, H. Y., Seng, Z., Xie, Y., Zhang, Y., Yang, L., Kwok, C. K. & Deng, X. RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria. mBio 11, 1 (2020).
2019
31. Ji, D., Li, Z., & Kwok, C. K. Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules. Analyst. 144, 7173 - 7177 (2019).
30. Lyu, K., Chen, S. B., Chan, C. Y., Tan, J. H., & Kwok, C. K. Structural analysis and cellular visualization of APP RNA G-quadruplex. Chemical Science. 10, 11095 - 11102 (2019).
29. Ji, D., Mou, X., Kwok, C.K. Label-free and ratiometric detection of microRNA based on target-induced catalytic hairpin assembly and two fluorescent dyes. Analytical Methods 11, 4808 - 4813 (2019).
28. Umar, M.I.; Ji, D.; Chan, C.-Y.; Kwok, C.K. G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications. Molecules 24, 2416 (2019)
27. Yeung, P.Y., Zhao, J., Chow, E.Y.C., Mou, X., Hong, H.Q., Chen, L.L., Chan, T.F., Kwok, C.K. Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Sci. Rep. 9, 8091 (2019)
26. Zhao, J., Qian, X., Yeung, P.Y., Zhang, Q.F.C., Kwok, C.K. Mapping In Vivo RNA Structures and Interactions. Trends Biochem. Sci. 44, 555-556 (2019)
25. Chan, C.-Y., Umar, M.I., Kwok, C.K. Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures. Chem Comm. 55, 2616-2619 (2019)
24. Qian, X., Zhao, J., Yeung, P.Y., Zhang, Q.F.C., Kwok, C.K. Revealing LncRNA Structures and Interactions by Sequencing-Based Approaches. Trends Biochem. Sci. 44, 33-52 (2019)
30. Lyu, K., Chen, S. B., Chan, C. Y., Tan, J. H., & Kwok, C. K. Structural analysis and cellular visualization of APP RNA G-quadruplex. Chemical Science. 10, 11095 - 11102 (2019).
29. Ji, D., Mou, X., Kwok, C.K. Label-free and ratiometric detection of microRNA based on target-induced catalytic hairpin assembly and two fluorescent dyes. Analytical Methods 11, 4808 - 4813 (2019).
28. Umar, M.I.; Ji, D.; Chan, C.-Y.; Kwok, C.K. G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications. Molecules 24, 2416 (2019)
27. Yeung, P.Y., Zhao, J., Chow, E.Y.C., Mou, X., Hong, H.Q., Chen, L.L., Chan, T.F., Kwok, C.K. Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Sci. Rep. 9, 8091 (2019)
26. Zhao, J., Qian, X., Yeung, P.Y., Zhang, Q.F.C., Kwok, C.K. Mapping In Vivo RNA Structures and Interactions. Trends Biochem. Sci. 44, 555-556 (2019)
25. Chan, C.-Y., Umar, M.I., Kwok, C.K. Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures. Chem Comm. 55, 2616-2619 (2019)
24. Qian, X., Zhao, J., Yeung, P.Y., Zhang, Q.F.C., Kwok, C.K. Revealing LncRNA Structures and Interactions by Sequencing-Based Approaches. Trends Biochem. Sci. 44, 33-52 (2019)
2018
23. Ziv, O., Gabryelska, M.M., Lun, A.T.L., Gebert, L.F.R., Sheu-Gruttadauria, J., Meredith, L.W., Liu, Z.Y., Kwok, C.K., Qin, C.F., MacRae, I.J., Goodfellow, I., Marioni, J.C., Kudla, G., Miska, E.A. COMRADES determines in vivo RNA structures and interactions. Nat Methods. 15, 785-788 (2018).
22. Chan, K.L., Peng, B., Umar, M.I., Chan, C.-Y., Sahakyan, A.B., Le, M.T.N., Kwok, C.K. Structural Analysis Reveals Formation and Role of RNA G-Quadruplex Structures in Human Mature MicroRNAs. Chem Comm. 54, 10878-10881 (2018).
21. Kwok, CK., Marsico, G., Balasubramanian, S. Detecting RNA G-quadruplexes (rG4s) in the Transcriptome. Cold Spring Harb Perspect Biol. 10:a032284 (2018).
20. Ding, Y., Kwok, CK. Emergence of Vascular Plants. Nature Plants 4, 325–326 (2018).
22. Chan, K.L., Peng, B., Umar, M.I., Chan, C.-Y., Sahakyan, A.B., Le, M.T.N., Kwok, C.K. Structural Analysis Reveals Formation and Role of RNA G-Quadruplex Structures in Human Mature MicroRNAs. Chem Comm. 54, 10878-10881 (2018).
21. Kwok, CK., Marsico, G., Balasubramanian, S. Detecting RNA G-quadruplexes (rG4s) in the Transcriptome. Cold Spring Harb Perspect Biol. 10:a032284 (2018).
20. Ding, Y., Kwok, CK. Emergence of Vascular Plants. Nature Plants 4, 325–326 (2018).
2017
19. Kwok, CK., Merrick, C.J. G-Quadruplexes: Prediction, Characterization, and Biological Application. Trends Biotechnol. 35, 997–1013 (2017).
18. Norris, M., Kwok, CK., Cheema J., Hartley M., Morris R.J., Aviran S., Ding, Y. FoldAtlas: A Repository for Genome-Wide RNA Structure Probing Data. Bioinformatics. 33, 306-308 (2017).
18. Norris, M., Kwok, CK., Cheema J., Hartley M., Morris R.J., Aviran S., Ding, Y. FoldAtlas: A Repository for Genome-Wide RNA Structure Probing Data. Bioinformatics. 33, 306-308 (2017).
2016
17. Kwok, CK., Dawn of the In Vivo RNA Structuome and Interactome. Biochem Soc. Trans. 44, 1395-1410 (2016).
16. Kwok, CK., Marsico, G., Sahakyan, A., Chambers V.S., Balasubramanian, S. rG4-Seq Reveals Widespread Formation of G-Quadruplex Structures in the Human Transcriptome. Nat. Methods. 13, 841-844 (2016).
15. Kwok, CK., Sahakyan, A., Balasubramanian, S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angew. Chem. Int. Ed. 55, 8958-8961 (2016).
14. Sherlock, M.E., Rumble, C., Kwok, CK., Breffke, J., Maroncelli, M., & Bevilacqua, P.C. Steady-State and Time-Resolved Studies into the Origin of the Intrinsic Fluorescence of G-Quadruplexes. J. Phy. Chem. B 120, 5146-5158. (2016).
16. Kwok, CK., Marsico, G., Sahakyan, A., Chambers V.S., Balasubramanian, S. rG4-Seq Reveals Widespread Formation of G-Quadruplex Structures in the Human Transcriptome. Nat. Methods. 13, 841-844 (2016).
15. Kwok, CK., Sahakyan, A., Balasubramanian, S. Structural Analysis using SHALiPE to Reveal RNA G-Quadruplex Formation in Human Precursor MicroRNA. Angew. Chem. Int. Ed. 55, 8958-8961 (2016).
14. Sherlock, M.E., Rumble, C., Kwok, CK., Breffke, J., Maroncelli, M., & Bevilacqua, P.C. Steady-State and Time-Resolved Studies into the Origin of the Intrinsic Fluorescence of G-Quadruplexes. J. Phy. Chem. B 120, 5146-5158. (2016).
2015
13. Crenshaw, E., Leung, B.P., Kwok, CK., Olson, K., Sebastian, N.P., Ansaloni, S., Schweitzer-Stenner, R., Akins, M.P., Bevilacqua, P.C., & Saunders, A.J. Amyloid Precursor Protein Translation is Regulated by a 3’UTR Guanine Quadruplex. PloS One. 10(11): e0143160. (2015).
12. Ding, Y., Kwok, CK., Tang, Y., Bevilacqua, P.C., & Assmann, S.M. Structure-Seq: Genome-Wide Profiling of In Vivo RNA Structure at Single Nucleotide Resolution. Nat. Protoc. 10, 1050-1066 (2015).
11. Tang, Y., Bouvier, E., Kwok, CK., Ding, Y., Nekrutenko, A., Bevilacqua, P.C., & Assmann, S.M. StructureFold: Genome-Wide RNA Secondary Structure Mapping and Reconstruction In Vivo. Bioinformatics. 31, 2668-2675 (2015).
10. Kwok, CK., & Balasubramanian, S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angew. Chem. Int. Ed. 54, 6751-6754 (2015). (Selected as Hot Paper.)
9. Kwok, CK., Tang, Y., Assmann, S.M., & Bevilacqua, P.C. The RNA Structurome: Transcriptome-Wide Structure Probing using Next-Gen Sequencing. Trends Biochem. Sci. 40, 221-232 (2015). (Featured on the cover)
8. Kwok, CK., Ding, Y., Shahid, S., Assmann, S.M., & Bevilacqua, P.C. A Stable RNA G-Quadruplex within the 5’UTR of Arabidopsis Thaliana ATR mRNA Inhibits Translation. Biochem. J. 467, 91-102 (2015). (Featured in HFSP website)
12. Ding, Y., Kwok, CK., Tang, Y., Bevilacqua, P.C., & Assmann, S.M. Structure-Seq: Genome-Wide Profiling of In Vivo RNA Structure at Single Nucleotide Resolution. Nat. Protoc. 10, 1050-1066 (2015).
11. Tang, Y., Bouvier, E., Kwok, CK., Ding, Y., Nekrutenko, A., Bevilacqua, P.C., & Assmann, S.M. StructureFold: Genome-Wide RNA Secondary Structure Mapping and Reconstruction In Vivo. Bioinformatics. 31, 2668-2675 (2015).
10. Kwok, CK., & Balasubramanian, S. Targeted Detection of G-Quadruplexes in Cellular RNAs. Angew. Chem. Int. Ed. 54, 6751-6754 (2015). (Selected as Hot Paper.)
9. Kwok, CK., Tang, Y., Assmann, S.M., & Bevilacqua, P.C. The RNA Structurome: Transcriptome-Wide Structure Probing using Next-Gen Sequencing. Trends Biochem. Sci. 40, 221-232 (2015). (Featured on the cover)
8. Kwok, CK., Ding, Y., Shahid, S., Assmann, S.M., & Bevilacqua, P.C. A Stable RNA G-Quadruplex within the 5’UTR of Arabidopsis Thaliana ATR mRNA Inhibits Translation. Biochem. J. 467, 91-102 (2015). (Featured in HFSP website)
2014
7. Ding, Y., Tang, Y., Kwok, CK., Zhang, Y., Bevilacqua, P.C. Assmann, S.M. In vivo Genome-Wide Profiling of RNA Secondary Structures Reveal Novel Regulatory Features. Nature. 505, 696-700 (2014). (Featured on the cover, F1000 site http://f1000.com/prime/718185620, Nature 505, 621-622 (2014), Nat. Meth.11, 11 (2014) and Nat. Chem. Biol. 10, 87 (2014).)
2013
6. Kwok, CK., Ding, Y., Tang, Y., Assmann, S.M., Bevilacqua, P.C. Determination of in vivo RNA Structure in Low-Abundance Transcripts. Nat. Commun. 4, 2971 (2013). (Featured in Nat. Meth.11, 11 (2014).)
5. Kwok, CK., Lam, SL. NMR Proton Chemical Shift Prediction of T∙T Mismatches in B-DNA Duplexes. J. Magn. Reson. 234, 184-189 (2013).
4. Kwok, CK., Sherlock, M.E. & Bevilacqua, P.C. Effect of Loop Sequence and Loop Length on the Intrinsic Fluorescence of G-Quadruplexes. Biochemistry 52, 3019-3021 (2013).
3. Kwok, CK., Ding, Y., Sherlock, M.E., Assmann, S.M. & Bevilacqua, P.C. A Hybridization-Based Approach for Quantitative and Low-Bias Single-Stranded DNA Ligation. Anal. Biochem. 435, 181-186 (2013). Featured on the cover.
2. Kwok, CK., Sherlock, M.E. & Bevilacqua, P.C. Decrease in RNA Folding Cooperativity by Deliberate Population of Intermediates in RNA G-Quadruplexes. Angew. Chem., Int. Ed. 52, 683-686 (2013). (Featured in F1000 site. http://f1000.com/prime/717970147.)
5. Kwok, CK., Lam, SL. NMR Proton Chemical Shift Prediction of T∙T Mismatches in B-DNA Duplexes. J. Magn. Reson. 234, 184-189 (2013).
4. Kwok, CK., Sherlock, M.E. & Bevilacqua, P.C. Effect of Loop Sequence and Loop Length on the Intrinsic Fluorescence of G-Quadruplexes. Biochemistry 52, 3019-3021 (2013).
3. Kwok, CK., Ding, Y., Sherlock, M.E., Assmann, S.M. & Bevilacqua, P.C. A Hybridization-Based Approach for Quantitative and Low-Bias Single-Stranded DNA Ligation. Anal. Biochem. 435, 181-186 (2013). Featured on the cover.
2. Kwok, CK., Sherlock, M.E. & Bevilacqua, P.C. Decrease in RNA Folding Cooperativity by Deliberate Population of Intermediates in RNA G-Quadruplexes. Angew. Chem., Int. Ed. 52, 683-686 (2013). (Featured in F1000 site. http://f1000.com/prime/717970147.)
2011
1. He, G., Kwok, CK. & Lam, SL. Preferential Base Pairing Modes of T.T Mismatches. FEBS Lett. 585, 3953-3958 (2011).